16 research outputs found

    08292 Abstracts Collection -- The Study of Visual Aesthetics in Human-Computer Interaction

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    From 13.07. to 16.07.2008, the Dagstuhl Seminar 08292 ``The Study of Visual Aesthetics in Human-Computer Interaction\u27\u27 was held in the International Conference and Research Center (IBFI), Schloss Dagstuhl. During the seminar, several participants presented their current research, and ongoing work and open problems were discussed. Abstracts of the presentations given during the seminar as well as abstracts of seminar results and ideas are put together in this paper. The first section describes the seminar topics and goals in general. Links to extended abstracts or full papers are provided, if available

    08292 Executive Summary -- The Study of Visual Aesthetics in Human-Computer Interaction

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    This seminar explored various aspects of the study of visual aesthetics in human-computer interaction (HCI). The discussed issues relating to theory building, measurement issues, antecedents of aesthetic design and its consequences. We also identified a set of research challenges that this emerging field needs to discuss

    Lessons on Combining Topology and Geography : Visual Analytics for Electrical Outage Management

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    Outage management in electrical networks is a complex task for operators and requires comprehensive overviews of the topology. At the same time valuable information for detecting the root cause may have geographical context such as digging activities or falling trees. Consequently, vendors of state-of-the-art SCADA systems started to integrate this valuable information source as well. However, in todays systems both views are separated, requiring operators to mentally connect the geographical and topological information. The wish of operators is to provide a comprehensive combination of both spaces in a single view. However, how to project geographical elements into the topology to support the workflow of real operators is yet unclear. In this paper, we present a design study for an interactive visualization system that provides a comprehensive overview for power grid operators. It provides full coverage of both spaces in order to measure how real operators make use of the geographical information. It bypasses the projection problem by interactive brushing-and-linking to support associative analysis. We extracted the mental-model of domain experts in real use cases and found a general bias source in sequential analysis of two spaces. We contribute our problem and task abstraction, lessons learned, and implications for future research.publishe

    Clinical Outcome and Quality of Life of Multimodal Treatment of Extracranial Arteriovenous Malformations: The APOLLON Study Protocol

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    Purpose Arteriovenous malformations (AVMs) as rare diseases are diagnostically and therapeutically challenging. Due to the limited evidence regarding treatment outcome, prospective data are needed on how different treatment regimens affect outcome. The aims of this prospective trial are to determine effectiveness, safety, and clinical outcome of multimodal treatment in patients with extracranial AVMs. Materials and Methods After clinical and magnetic resonance imaging (MRI)-based diagnosis and informed consent, 146 patients (> 4 years and < 70 years) undergoing multimodal therapy in tertiary care vascular anomalies centers will be included in this prospective observational trial. Treatment options include conservative management, medical therapy, minimally invasive image-guided procedures (embolization, sclerotherapy) and surgery as well as combinations of the latter. The primary outcome is the patient-reported QoL 6 months after completion of treatment using the short form-36 health survey version 2 (SF-36v2) and the corresponding short form-10 health survey (SF-10) for children. In addition, clinical presentation (physician-reported signs), MRI imaging (radiological assessment of devascularization), recurrence rate, and therapeutic safety will be analyzed. Further follow-up will be performed after 12, 24, and 36 months. Moreover, liquid biopsies are being obtained from peripheral blood at multiple time points to investigate potential biomarkers for therapy response and disease progression. Discussion The APOLLON trial is a prospective, multicenter, observational open-label trial with unequal study groups to generate prospective evidence for multimodal treatment of AVMs. A multicenter design with the potential to assess larger populations will provide an increased understanding of multimodal therapy outcome in this orphan disease

    NUCLEAR NONHISTONE PROTEINS: CHEMISTRY AND FUNCTION

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